노인인구에서 평생 알코올 소모와 인지기능과의 관계: 교육수준에 따른 효과 수정

Relationships between Lifetime Alcohol Consumption and Cognitive Function in an Elderly Population: Effect Modification by Level of Education

Objective: The relationship between lifetime alcohol consumption and cognitive function in an elderly population has been unclear. This study aimed to investigate, 1) the relationship between alcohol consumption and cognitive function, and 2) possible effect modification in the relationship by level of education. Methods: The study group consisted of 106 community dwelling old men aged 65 or over, who were divided into two subgroups : with (0=75) and without (0=31) formal education. Life-long duration and amount of alcohol consumption, and cognitive function (Korean version of Mini-Mental State Examination ; MMSE-K) were assessed, and the relationships between the variables were estimated by Spearman's rho. Results: No significant differences were found in life-long duration and amount of alcohol consumption between the subgroups with and without education. However, relationships between alcohol consumption and cognitive function differed between the subgroups. No correlations were observed in the subgroup with education. However in the subgroup without education. the longer duration and larger amount of alcohol consumption were significantly correlated with lower scores on the MMSE-K, Conclusion : The elderly population with low levels of education may be particularly vulnerable to cognitive impairment related with life-long alcohol consumption. (Korean J Psychopharmacol 2003; 14(3):239-243)