일부 젊은 연령층의 인유두종바이러스(Human Papillomavirus) 감염 위험요인간의 관련성 연구

Relationship among risk factors related to Human Papillomavirus infection among youth

Purpose : To investigate the prevalence and related risk factors of infection with human papillomavirus(HPV) in young adults, and the interrelationships among the risk factors, school-based survey was conducted in Busan. Methods : A total of 1,430 male and female students(aged 16-25) participated in the survey that included self-administered questionnaire and, for males, physician-performed collection of exfoliated genital cells, for females, selfcollection of vaginal cells. The prevalences of 25 HPV types were evaluated by a polymerase chain reaction-based assay. Results : HPV DNA detected more frequently in female students(l5.2%) than in male students(8.7%). In female students, currently smoking cigarettes(OR=3.8, 95% CI=1.7~8.3) and having had penetrative sexual intercourse(OR=12.7, 95% CI=7.2~22.2) were the significant risk factors for HPV infection; in male students, there was nothing to show statistical significance. Smoking rate was 53.8% in males and 17.7% in females, and 55.6% of male students and 25.9% of female students reported having had a sexual intercourse. Smokers were more likely to have had a sexual intercourse than nonsmokers(OR=4.0, 95% CI=2.5~6.2, males; OR=9.1, 95% CI=5.6`14.7, females). Conclusions : According to the strong interrelationship between sexual intercourse and smoking, multilateral behavioral intervention is needed to prevent infection with HPV.