운동수행시 혈청효소 변화 분석

Change in serum enzyme following acute physical exercise

&nbsp;&nbsp;This study aim to compare the effects of acute physical exercise on the serum enzyme, Creatine phosphokinase(CPK), Lactate dehydrgenaes(LDH), glutamic axaloacetic transaminase(GOT) and glutamic pyruvic transaminase(GPT) in two groups of Body Mass Index. The subject was diveded two groups of 8 normal(BMI＜23) and 8 obesity (BMI＞30).<BR>&nbsp;&nbsp;The exercise consisted of running on a mater driven-treadmill until the subject reached exhaust. Blood sample were drawn from the antecubital vein before, immediately after exercise, postexercise 30 minute and postexercise 60 minute.<BR>&nbsp;&nbsp;Serum enzyme activity increase immediately after exercise the end of the tradmill test in the both groups for CPK(24.5%), LDH(15.3%), GOT(39.0%), and GPT(20.6%), and gradually decrease postexercise 60 minute to approximately to base activity.<BR>&nbsp;&nbsp;The serum enzyme activity significantly different between normal and obesity groups in before exercise of CPK(40.8%), LDH(14.7%), GOT(27.&amp;%), and GPT(72.4%)(p＜0.05), and the immediately after exercise activity nonsignificantly different for CPK(29.0%), LDH(2.9%), GOT(8.1%), but GPT is significantly different(p＜0.05).<BR>&nbsp;&nbsp;It is concluded from this study that serum enzyme activity rise after exercise and recover to the base activity after postexercise 30 and 60 minute. It is indicate that serum enzyme release to blood from skeletal muscle, tissue and organ. Obesity group&quot;s serum enzyme activity more higher than normal group is important pathologicl examination especially GOT, GPT.