정상인 집단과 성인병 집단의 심폐기능과 혈액성분에 관한 연구

The Study of Cardiorespiratory Function and Blood Components in Normal and Degenerative Diseases Groups

&nbsp;&nbsp;To study effects of cardiorespiratory function and blood components in normal and degenerative disease groups, 36 men who aged 40-60yrs were checked by medical process and exercise stress testing. Subjects were divided into five groups that were control, activity, obesity, hypertension and diabetes group.<BR>&nbsp;&nbsp;Results of this study are following,<BR>&nbsp;&nbsp;1. %Body fat is 19.7% in control groups, 17.4% in activity group, 30.1% in obesity group, 26.0% in hypertension group and 27.1% in diabetes group. Control and activity group are significantly leaner than obesity, hypertension and diabetes group(p＜0.05).<BR>&nbsp;&nbsp;2. It is not significantly different in amounts of WBC and RBC between groups. But obesity group has a significantly more amount of hemoglobin than control group(p＜0.05).<BR>&nbsp;&nbsp;3. Glucose is 164.83㎎/㎗ in diabetes group, which is the significantly most plentiful among groups(p＜0.05). But in Calcium and Pi, it is not significantly different between groups.<BR>&nbsp;&nbsp;4. In serum cholesterol, total cholesterol is 179.0㎎/㎗ in activity group, which is the significantly least amount among groups(p＜0.05). LDL-C(101.3㎎/㎗) and triglycerides(135.5㎎/㎗) of activity group are the significantly least amount among groups, too(p＜0.05). Amount of HDL-C of activity group is greater than obesity, hypertension and diabetes group, but not significant.<BR>&nbsp;&nbsp;5. Resting HR is 60.6beats/min in control group and 57.1beats/min in activity group, that are significantly lower than those of hypertension and diabetes(p＜0.05). Resting SBP/DBP is 160.7/107.9㎜Hg in hypertension group, which is the highest among groups(p＜0.05), but blood pressure of other groups are normal.<BR>&nbsp;&nbsp;6. Resting rate pressure product(RPP ; myocardial oxygen consumption) is 6.60×103㎜Hgㆍbpm in activity group, which is less than those in obesity, hypertension and diabetes group(p＜0.05). Values of hypertension group, 10.91×103㎜Hgㆍbpm, are the greatest among others(p＜0.05).<BR>&nbsp;&nbsp;7. Maximal oxygen consumption(？o2max) of activity group is 37.3㎖/㎏/min, that is significantly greater than degerative groups(p＜0.05).<BR>&nbsp;&nbsp;8. Correlation coefficients with ？o2max have significance(p＜0.001); TCH(r=-0.853), HDL-C(r=0.633), LDL-C(r=-0.813), Triglycerides(r=-0.844), TCH/HDL-C (r=-0.862), LDL-C/HDL-C (r=-0.834).<BR>&nbsp;&nbsp;9. Correlation coefficients with resting RPP have significance; (p＜0.001) TCH(r=0.732), LDL-C(r=0.699), Triglycerides(r=0.705), TCH/HDL-C(r=0.736), LDL-C/HDL-C (r=0.713); (p＜0.001) HDL-C(r=-0.483).<BR>&nbsp;&nbsp;Results of this study indicate that improvement of cardiorespiratory function induces significant changes of serum lipids in middle and elderly men, implicate that modern degenerative diseases are decrease according to cardiorespiratory function. Conclusionally, elderly men must increase their activities in daily life for improving their cardiorespiratory function and protecting degenerative disease. This study is expected to contribute the area of exercise prescription, hereafter more effort is required to establish the relation between serum lipids and exercise amount.