학술저널
Dynamic Thermodynamic Resolution - Solvent Effects, Mechanism, and an Asymmetric 3,4,5-Substituted Benzazepine Synthesis
Dynamic Thermodynamic Resolution
- 충남대학교 소재화학연구소
- 소재화학연구소 논문집
- 제2호
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2007.01132 - 135 (4 pages)
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〈그림 참조〉<BR> The resolution in the lithiation-substitution sequence from 1 to 4-11 in MTBE is shown to be under thermodynamic control In contrast to the previous report of kinetic control In dlethyl ether. Diastereomeric equilibration of a soluble complex is shown to be controlling and an asymmetric synthesis of a 3,4,5-substituted benzazeplne Is reported.
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