운동과 Adipokine과의 관계

Relative on Exercise and Adipokine

&nbsp;&nbsp;Adipose tissue is a complex, essential, and highly active metabolic and endocrine organ. Besides adipocytes, adipose tissue contains connective tissue matrix, nerve tissue, stromovascular cells, and immune cells. Adipose tissue not only responds to afferent signals from traditional hormone systems and the central nervous system but also expresses and secretes factors with important endocrine functions. Also, adipose tissue is not merely a fat storage depot, but has been recognized as an endocrine organ capable of producing biologically active proteins termed "adipokines".<BR>&nbsp;&nbsp;Obesity is a major risk factor for type 2 diabetes and cardiovascular disease, and adipocyte-derived factors might contribute to or ameliorate obesity-associated pathologies such as insulin resistance, dyslipidemia, vascular dysfunction and a chronic inflammatory and prothrombotic state. Consequently, insulin resistant and type 2 diabetes is that changes in circulating adipokine levels are involved in the improvement of the metabolic state by moderate exercise time, intensity, frequency.