계피식이가 고지혈증 유도 흰쥐의 지질대사 및 혈소판 응집에 미치는 영향

Effects of Dietary Cinnamon on Lipid Metabolism and Platelet Aggregation in Hyper-Cholesterolemic Rats

  The purpose of the present study was to investigate effect of dietary cinnamon on serum lipids and platelet aggregation in hyper-cholesterolemic rats. Sprague-Dawley rats were fed with hyper-lipidemic diet for 4 weeks in order to induce hyper-lipidemia, followed by feeding experimental diets for additional 4 weeks. Cinnamon in experimental diets was prepared by drying and milling. Cinnamon powder was added to experimental diets at the level of 2% and 5%. ALT and AST was significantly decreased in both cinnamon 2% and cinnamon 5% groups compared to control group. HDL-cholesterol was increased significantly while LDL-cholesterol was significantly decreased in both cinnamon 2% and 5% groups. Platelet aggregation was decreased significantly in cinnamon 5% group. The present observation indicates that cinnamon might be helpful for the prevention and treatment of hyper-lipidemia and platelet aggregation.