비타민-C 이온영동법 관리의 피부미백효과

Whitening Effects of Facial Skin by Using Vitamin-C Iontophoresis Treatment

&nbsp;&nbsp;Whitening effects by using vitamin-C iontophoresis have been evaluated with change of skin reflectance of the CIELAB color space. However, CIELAB in the tristimulus colorimeter could not detect the slight difference such as visual effects in skin color when using whitening cosmetics. We have developed a new evaluation method of change of skin color using computer analysis of the CCD(charge coupled divice)-captured noncompressed digital image(TIFF). We have also investigated whitening effects by using vitamin-C iontophoresis on skin color of the face in 10 healthy female volunteers. Measurement was performed after 4 weeks application. Whitening effects were also evaluated with the observation and photographs.<BR>&nbsp;&nbsp;Vitamin-C iontophoresis application showed significant improvement in the L*, a*, b*values, which was used to measure skin color, and subjective judgement. The results by a statistical analysis also allowed the statistic significance at L*(Lightness) of the forehead and right cheek and a*(erythema) of the right cheek in spite of a short-term.<BR>&nbsp;&nbsp;This image analysis allowed us to study skin areas, to take measurements without any contact with the skin, and to analyze the image pixel by pixel, providing quantitative information according to localization. Consequently this promising quantitative method may enable objective measurement of skin color changes to be made, and allow evaluation of the skin efficacy without the inherent errors associated with subjective judgement.