좌측 측두엽에 방사선 괴사가 발생한 뇌간 교종 1례

A case of Pontine glioma with radiation necrosis on left temporal lobe

Cerebral radiation necrosis is classified according to the time of appearance of symptoms after therapy. Acute injury appears during radiation therapy as a transient worsening of symptoms and has little prognostic significance. Early delayed injury occurs a few weeks to 3 months after therapy and also is transient in most cases. By contrast late radiation injury, which occurs a few months to 10 or more years after therapy, is irreversible, progressive, and sometimes fatal, and constitutes the major, dose-limiting complication of cerebral irradiation. There are two main forms of late radiation injury : focal necrosis and diffuse white matter injury. Authors experienced a case of pontine glioma with radiation necrosis on left temporal lobe about 2 months after radiation therapy of total 4300rad. We presented this case with a brief review of literatures.