Benign epilepsy of childhood with centrotemporal spikes에서 간질성 발작파 초점의 발생위치

LOCATION OF EPILEPTIFOM DISCHARGE IN BENIGN EPILEPY OF CHILDHOOD WITH CENTROTEMPORAL SPIKES

Background: Although benign epilepsy of childhood with centrotemporal spikes ( BECCT ) is an electroclinical syndrome originally based on EEG epileptiform discharges localized to the centrotemporal area, the occurrence of typical clinical manifestations in chidren with atypical foci have been reported by several authors. The aim of this study was to identify the importance of the epileptiform discharge location in BECCT. Method: We reviewed EEGs from children whose history and clinical manifestation compatible with BECCT to identify the occurrence of typical clinical manifestation in patient with atypical foci of epileptiform discharge. Result: 1) The age of seizure onset were 3 to 13 years old (mean.7.3 ) and male to female ratio was 1.2 : 1. 2) 22.0% of patients had more than two independent epileptiform discharge foci. 3) 78.1% of patients with single focus had typical central and midtemporal foci, and 21.9% had atypical poci, and epileptiform discharge foci were central(40.6%), midtemporal(37.5%), parietal (15.6%),occipital(3.1%), frontal(3.1%) inorder of frequency. 4) Although atypical foci revealed in younger age group, there was no static significance (P>0.1). We conclude that the normal background features, the typical morphology of epileptiform discharge, and the activation by sleep are the typical EEG features of this syndrome, and the cases should not be exclude who demonstrate typical features of BECCT except centrotemporal location of epileptiform dischage.