양성신생아 경련 2례

Two Cases of Benign Non - Familial Neonatal Convulsion

저자들은 신생아 경련을 보인 환아들에서 드문 간질 증후군인 양성 신생아 경련을 경험하였기에 보고하는 바이다. 양성 신생아 경련은 항경련제의 장기간 사용이 불필요하므로 이에 대한 경험이 신생아 경련 치료에 도움을 줄 수 있을 것으로 생각된다.

Benign idiopathic neonatal convulsion is a rare disorder which has no family history of convulsion and develops before and after the 5th day in a healthy full-term neonate. Its characteristics appear focal, or multifocal clonic seizures but rare tonic seizures lasting about several minutes. It reveals non-specific findings in neurologic examination, neuroimaging and EEG(electroencephalography) so that it should be differentiated from those diseases such as eletronic imbalance, inborn errors of metabolism, other neonatal epileptic syndromes. We report two healthy full-term female neonates presented with multifocal clonic seizures before and after the 5th day after birth. They had no family history of convulsion, fetal asphyxia, fetal and maternal problems and the neurologic examination and neuroimagings were normal. The convulsions were controlled by intravenous phenobarbital injection. They had no more convulsions ever since and showed normal development at the follow-up performed one year later. We experienced a rare disorder, benign neonatal convulsion in healthy full-term neonates. We hope this report will help its diagnosis and treatment and prevent unnecessary long- term anticonvulsant medication.