Short-Term Results of Non-Small cell Lung Cancer with Curative Radiotherapy

1985년 8월부터 1988년 10월까지 전남대학교병원 치료방사선과에서 근치목적의 방사선치료를 받은 비소세포성 폐암환자 102명에 대하여 후향적 분석을 시행하였다. 대상환자들에 대한 추적조사기간은 1개월에서 37개월이었고 중간값은 15개월이었다. 전체환자군의 1년 및 2년 생존율은 각각 28%, 5%였으며 임상적 병기별로 보면Ⅱ, ⅢA, ⅢBrl 환자군의 평균생존기간은 각각 10개월, 6개월, 9개월이었고 2년 생존율은 각각 12.5%, 12.1%, 0%였다. 방사선치료후 치료실패가 확인된 32명에 대하여 분석을 하여보면 국소실패군이 28%(9명)였으며 원격실패군이 72%(23명)로 폐암환자의 사망의 대부분은 전신적인 원격전이에 의함을 알 수 있었다. 치료당시의 전신적 건강상태는 생존율에 유의한 영향을 주었으나(p<0.01), 방사선 치료선량에 따른 생존율의 유의한 차이는 보이지 않았다(p>0.05).

A retrospective analysis was performed on 102 patients with non-small cell lung cancer who received the curative radiotherapy from August 1985 to October 1988 at the Department of Therapeutic Radiotherapy of Chonnam University Hospital. The follow-up period was ranged from 1 to 37 months and the median follow-up time was 15 months. The actuarial 1 and 2 year survival rate of all the patients was 28% and 5%, respectively. The median survival was 10 months for stage Ⅱ, 6 months for stage ⅢA, and 9 for ⅢB and the actuarial 2 year survival tate was 12.5%, 12.1% and 0% respectively. The treatment failure was identified in 32 patients and the locoregional failure was seen in 9 patients (28%) and the distant failure in 23 patients (72%). The initial performance status was relates to the survival with statistical significance (p<0.01), but the survival difference by the radiation dose was not statistically significant (p>0.05).