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Squamous Cell Carcinoma of the Supraglottic Larynx Treated with Radiation Therapy

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Sixty-six patients with squamous cell carcinoma of the supraglottic larynx received irradiation with curative intent between 1979 and 1985 were retrospectively analysed. All patients had a minimum follow-up of 4 years. Of the entire group consisting of 73% T3 and T4 lesions and 58% lymph node metastases, a 5-year acturial survival rate was 31.3%. A 5-year acturial survival rates for stage Ⅱ, Ⅲ and Ⅳ were 60.7% respectively (p<0.05). Patients without lymphnode metastases had better survival rate than those with postive lymphnode metastases (54.8% vs 12.2%) (p<0.005). Surgical salvage rate w8s 4/7(57%). Three patients developed distant metastases. Major complications requiring surgery were seen in , Radiation therapy alone with surgical salvage was an effective, voice preserving treatment for stage Ⅰ, Ⅱ and selected Ⅲ carcinoma of the supraglottic carcinoma, however planned combined treatment with surgery and radiation therapy is advised for stage Ⅲ and Ⅳ carcinoma of the supraglottic larynx with resectable neck disease.

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