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학술저널

녹차 첨가식이가 칼슘 결핍 난소절제 쥐의 골밀도 및 골함량에 미치는 영향

Effects of Green Tea Powder on Bone Mineral Density and Bone Mineral Content in Ovariectomized Rats Fed Calcium-deficient Diet

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The purpose of this study was to investigate the effects of green tea powder on bone metabolism in ovariectomized rats (Ovx) fed a calcium-deficient diet. Twenty-one female Sprague-Dawley rats (body weight 200 ± 5 g) were divided into three groups: Sham, Ovx control (Ovx-C) and Ovx green tea powder (Ovx-GTP). Each group was randomly divided into control and test subgroups, the latter of which was fed a green tea powder-supplemented diet. All rats were fed an experimental diet and deionized water ad libitum for 6 weeks. Bone mineral density (BMD) and bone mineral content (BMC) were estimated by using PIXImus (GE Lunar Co, Wisconsin, USA) in the spine and femur after feeding. The results obtained in this study are summarized as follows. The body weight gain and food efficiency ratio (FER) were significantly higher in the Ovx groups than in the Sham control group, regardless of diet. Spine BMD, spine BMD per body weight and spine BMC per body weight were significantly lower in the Ovx groups than in the Sham control group. However, there was no significant differences according to green tea powder intake. In addition, there were no significant differences in spine BMC, femur BMD or femur BMC among all test groups. Femur BMD per body weight and femur BMC per body weight were significantly lower in the Ovx groups than in the Sham control group.

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