학술저널
Proapoptotic role of nuclear clusterin in brain
- 대한해부학회
- Anatomy and Cell Biology
- Vol.44(3)
-
2011.09169 - 175 (7 pages)
- 42
커버이미지 없음
Clusterin (CLU) is a multifunctional glycoprotein that has secretory and nuclear isoforms. The two isoforms are known to play opposite roles in cell survival/death. In this review, we summarize recent progress on the pro-apoptotic function of nuclear CLU in vitro and in vivo and discuss previous reports on the role of CLU in brain damage and neurodegeneration.
Abstract
Introduction
Proapoptotic Role of nCLU
CLU in Brain Damage and Neurodegeneration
Concluding Remarks
Acknowledgements
References
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