유용성감초추출물을 함유하는 나노에멀젼의 특성에 관한 연구

Study of the properties of oil-soluble licorice extract nano-emulsion

Over the course the past few years, many people have been attracted by functional cosmetics, pharmaceuticals and food, resulting in much study in the academic and industrial fields to enhance the stability of active ingredients under the effects of light, heat and oxygen, etc. Oil-soluble licorice extract is a functional whitening material the color stability of which depends on environmental factors such as temperature, oxygen and light. The basic purpose of cosmetics containing active ingredients is to develop formulation technologies that stabilize active compounds in the skin and to deliver effective materials selectively to the skin. In this study, the stability and skin penetration of oil-soluble licorice extract are improved by nano-emulsion. To evaluate the effect of nano-emulsion, physical properties such as droplet size and size distribution were examined. Oil-soluble licorice extract nano-emulsion was obtained using a microfluidizing process at 800bar resulting in a micelle size in the nano-emulsion solution in the 10-100nm range. According to chromameter data, the color stability of the nano-emulsion was enhanced 2 ~ 5 times compared with a general cream. The effect of skin penetration was improved, as well.