녹차분말 첨가식이가 고콜레스테롤 식이를 섭취한 흰쥐의 혈중 지질과 항산화효소 활성에 미치는 영향

Effects of Green Tea Powder Supplements on Serum Lipids and Antioxidant Enzymes in Growing Male Rats Fed a High Cholesterol Diet

The purpose of this study was to investigate the effect of green tea powder on serum lipids and antioxidant enzymes in growing male rats fed a high cholesterol diet. Sixteen male Sprague-Dawley rats (3 weeks old) with a high cholesterol diet were divided into two groups : the control group and the green tea powder-supplement group (1%/diet). All of the rats in this study had been fed on refined diets with green tea powder (1%/diet) based on AIN-93G for nine weeks. There were no significant differences in the body weight gain, food intake or food efficiency ratio between the control and green tea powder-supplement group. The total cholesterol and LDL-cholesterol levels as well as the atherogenic index were significantly lower in rats fed the green tea powder than in those fed the control diet. Antioxidant enzymes in liver tissue such as superoxide dismutase, catalase, and glutathione peroxidase were significantly higher in the green tea powder-supplement group. There were no significant differences in malonaldehyde in liver tissue between the control and green tea powder-supplement groups. In conclusion, this study indicated that green tea powder consumption positively influenced blood lipid content and antioxidant activity. Further study is needed to provide a more definitive conclusion concerning whether or not the routine consumption of green tea powder can guard against hyperlipidemia in human.