This study was carried out to investigate the biological activities, including the total polyphenolic contents, antioxidant activities, and tyrosinase inhibitory activities, of methanol extracts of five fruit teas (Lycium chinense, Cornus officinalis, Schizandra chinensis, Cassia tora, and Rubus coreanus). For tyrosinase inhibitory activities, C. tora extract showed the highest inhibitory activity. The results indicate that total phenolic content was the highest in R. coreanus among the fruit teas, whereas it was lowest in S. chinensis. For DPPH and ONOO― scavenging activities, fruit teas showed potent antioxidant activities in a dose-dependent manner. The IC50 values of fruit teas were as follows: 909.04 ± 5.79, 38.56 ± 0.77, 847.21 ± 1.27, 43.86 ± 0.67, and 6.68 ± 0.07 μg/mL in DPPH assay (positive control, L-ascorbic acid, IC50 1.66 ± 0.02 μg/mL) and 39.82 ± 0.83, 6.53 ± 0.11, 139.42 ± 2.22, 4.27 ± 0.30, and 0.44 ± 0.13 μg/mL in ONOO― assay (positive control, L-penicillamine, IC50 1.13 ± 0.06 μg/mL). These result will be useful for the application of functional foods and for understanding the physiological activities of fruit teas.
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