삼백초 추출물의 항균성과 두피에 미치는 영향

Antimicrobial Activity and Impact on Scalp of Saururus Chinensis Baill Extract

Some medicinal plant have been used to beauty care such as dandruff. In this study, antimicrobial activity of Saururus chinensis Baill extracts against Malasezia furfur (fungi caused dandruff), Pityrosporum ovale (fungi caused dandruff), Propionibacterium acne (bacteria caused pimple), Staphylococcus aureus (gram positive bacteria), Echerichia coli(gram negative bacteria) and Bacillus subtillis (gram negative bacteria) using turbidity of liquid broth, paper disc diffusion and spreading of agar plate. In turbidity of liquid broth, each microorganism showed antimicrobial activity with S. chinensis extracts of >7%. E. coli showed clear zone of 6.08 mm with S. chinensis extracts of 50% and B. subtilis exhibited clear zone of 6.70 mm with S. chinensis extracts of 90% in paper disc diffusion. Furthermore, clear zone was 7.20 mm for S. aureus, 6.33 mm for P. ovale, 7.30 mm for P. acne in 90% of S. chinensis extracts. In spreading of agar plate, E. coli showed antimicrobial activity at 7% of S. chinensis extracts and B. subtillis, M. furfur and P. acne exhibited antimicrobial activity at 25% of S. chinensis extract. In clinical test, 10 subjects didn’t appeared allergic reactions were treated with shampoo blending aroma oils and 15 drops of 50% concentration of S. chinensis extract for 4 weeks and degree of change on dandruff and inflammation of before and after of treatment evaluated by expert. Degree of change on dandruff and inflammation of experiment groups treated with the shampoo changed for the better than before treatment and control groups. Therefore, S. chinensis extracts were contained antimicrobial compounds and it may be suitable to develop new antimicrobial agents for care of hair diseases from these sources.