유전성 경직성 하반신마비 증례보고

A case Report of Hereditary Spastic paraparesis

Hereditary spastic paraparesis (HSP), or Strumpell-Lorrain syndrome, is a heterogenous group of hereditary neurodegenerative disorder of the central nervous system in which the primary clinical manifestation is a slowly progressive bilateral, spastic paraparesis. This paper is reporting a case of pure hereditary spastic paraparesis, which is the onset were 26 years ago. Physical examination revealed normoactive deep tendon reflexs in all four extremities with extensor plantar reflex and equinus. Electrodiagnostic study revealed no electrophysiological abnormality. The mode of inheritance of were autosomal dominant and were consistant those of type I of Harding's classification.