학술저널
우라자미드 정의 유해시약 대체 시험법의 개발
Development of Alternative Assay Method without Hazardous Reagent, Chloroform for Urazamide Tablets in Korean Pharmaceutical Codex
- 대한약학회
- 약학회지
- 제58권 제2호 (2014년)
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2014.04125 - 128 (4 pages)
- 6
We developed an alternative assay method without hazardous reagent of chloroform for urazamide tablets in Korean Pharmaceutical Codex. The HPLC analytical method was validated by system suitability, linearity, precision, accu-racy and robustness. The linearity of the calibration curves in the desired concentration range is good (r 2 >0.999). Precision was obtained less than RSD 1.17%. Accuracy was obtained with recoveries in range of 98.12% and 99.47%. The developed assay could be expected to become valuable tools for revising the Korean Pharmaceutical Codex.
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