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ORD 및 CD에 의한 Tropane Alkaloid의 정량에 관한연구(I)

Studies on the Determination of Hyoscine-N-butylbromide by ORD and CD(I)

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The ORD and CD for hyoscine-N-butylbromide present curves of negative Cotton effect in 190~250nm region. The values of alpha232, alpha2O8, |alpha232|+|alpha2O8| and theta221.5 have linearities in the range of lower concentration (hyoscine-N-butylbromide 0.01-0.lw/v%). It is possible to determine the optical purity of hyoscine-N-butvlbromide by using these linearities. This experiment is extremely simple and less time-consuming than other methods for estimating optical purity.

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