학술저널
실험 항암제 2-Formylpyridine Thiosemicarbazone유도체의 철 및 동착물의 합성
Synthesis of Iron and Copper Complexes of 2-Formylpyridine Thiosemicarbazone Derivatives, Potential Antitumor Agents
- 대한약학회
- 약학회지
- 제26권 제3호 (1982년)
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1982.09181 - 184 (4 pages)
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The iron and copper chelates of 4-dimethylamino-2-formylpyridine thiosemicarbazone, one of the amine substituted derivatives at 4-C of 2-formylpyridine thiosemicarbazones which are known as the more improved potential antitumor agents, have been synthesized to make them more effective than the ligand (denoted as HL) itself. Their ligand-to-metal ratios were 2:1 and 1:1 for the iron and copper chelates, and the data along with those of elemental analysis and IR spectroscopy showed that the compositions are [FeL2].2H2SO4 and [CuL(H20)]Cl, respectively.
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