이온대 화합물의 참분배계수가 추출정수 결정에 미치는 영향

Effect of True Partition Coefficient on the Determination of Extraction Coefficient of Ion-Pair Complexes

Whether [ABW] may be neglected against [AW+] in the calculation of the extraction coefficient of ion-pairs was criticized by both experiments and theoretical consideration, where [ABW] and [AW+] mean the molar concentration of ion-pair AB and cation A+ in the aqueous phase. Ion-pair complexes were partitioned between phosphate buffer (pH 7.4) and n-octanol. Tetrabutylammonium, isopropamide and metbylene blue were selected as cations and benzoic acid, p-toluenesulfonic acid, salicylic acid and taurodeoxycholic acid were selected as counter ions (anions). As a result, conventional methods which assume no existence of [ABW] were proven to lack generality. The equation proposed in my earlier report was confirmed to be valid as a general method.