학술저널
Piperine유도체의 합성 및 중추억제작용에 관한 연구(II) Piperic Acid Amide 유도체
Syntheses and Central Nervous Depressant Activities of Piperine Derivatives (II) Piperic Acid Amides
- 대한약학회
- 약학회지
- 제27권 제4호 (1983년)
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1983.12283 - 287 (5 pages)
- 2
In order to search more active and less toxic central nervous depressants, piperic acid amides were synthesized by condensation of piperonal with crotonic acid amides. The bioassay results revealed that, among the compounds synthesized, the piperonic acid methylamide and ethylamide exhibited potent protective activity against strychnine-induced convulsion.
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