학술저널
GC/FPD를 이용한 beta-락탐계 항생물질의 분석(I)
Determination of beta-Lactam Antibiotics by Gas Chromatography with Flame Photometric Detector (I)
- 대한약학회
- 약학회지
- 제28권 제1호 (1984년)
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1984.0225 - 27 (3 pages)
- 23
Some beta-lactam antibiotics penicillins and cephalosporins were determined by gas chromatography (GC) with flame photometric detector (FPD) which was selective and sensitive to sulfur-containing compounds. Methyl ester derivatives of carboxyl group in beta-lactam antibiotics were prepared using 0.5M-methyl iodide in methylene chloride and were taken for gas chromatography with 0.9% or 0.6% QF-1 on Chromosorb WAW-DMCS. We have found that it is possible to determine methyl esters of beta-lactam antibiotics by GC/FPD.
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