학술저널
Tranylcypromine의 겉보기 해리항수 및 분배계수
Apparent pKa and Partition Coefficient of Tranylcypromine
- 대한약학회
- 약학회지
- 제28권 제5호 (1984년)
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1984.10293 - 297 (5 pages)
- 3
The pKa'' of tranylcypromine was determined by potentiometric titration and ultraviolet spectrophotometric method and found to be 8.08 and 8.15, respectively. The Papp of tranylcypromine between n-heptane and aqueous buffer solution was measured to be 0.90 at pH 7.48 and 4.50 for Pm. The pKa'' of tranylcypromine obtained by means of the partition method was 8.13.
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