학술저널
Sodium 5-Methoxy Salicylate의 흡수촉진 효과에 관한 연구(II) 흡수촉진제에 대한 반응성
A Study on the Absorption Enhancing Effect of Sodium 5-Methoxysalicylate(II) -On the Activity of the Absorption Enhancing Agent-
- 대한약학회
- 약학회지
- 제30권 제2호 (1986년)
-
1986.0496 - 99 (4 pages)
- 3
Absorption enhancing effect of 5MSA-Na at the mucous membranes of the rectum and duodenum was studied via in vitro sac test. There were no significant differences between two membranes. Effect of 5MSA-Na on the transfer of CMZ to the tissue was also studied via in situ loop method. There was no significant difference at the duodenum, compared to the control when CMZ was administered intravenously. Transfer of CMZ to the loop of the rectum was increased in the presence of 5MSA-Na compared to the control, which might be attributed to the enhanced permeability of the mucous membrane of the rectum.
(0)
(0)