학술저널
나프록센의 Alkanol 에스테르류에 관한 생물약제학적 연구 I - 3종의 Alkanol 에스테르의 합성 -
Biopharmaceutical Studies on the Alkanol Esters of Naproxen(I) - Synthesis of 3 Kinds of the Alkanol Esters of Naproxen -
- 대한약학회
- 약학회지
- 제30권 제3호 (1986년)
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1986.06121 - 127 (7 pages)
- 4
Three new alkanol esters of d-2-(6-methoxy-2-naphthyl)propionic acid, NAPROXEN were synthesized by esterification of sodium naproxen with chloralcohols, such as 2-chloroethanol, 3-chloro-1, 2-propanediol and beta-chloroethoxyethanol in dimethylformamide. These new esters were obtained with comparably high yield and identified by elemental analysis, UV, IR and NMR techniques.
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