학술저널
벤조펜안드리딘과 관련된 알칼로이드의 합성
Synthesis of Benzophenanthridine-Related Alkaloids
- 대한약학회
- 약학회지
- 제36권 제3호 (1992년)
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1992.06250 - 254 (5 pages)
- 7
Benzo[C]phenanthidine alkaloids were found to exhibit considerably strong antileukemic activies. These alkaloids have been shown to be biosynthesized from the corresponding alkaloids throung an oxidative C6-N bond cleavage followed by recyclization between C6 and C13 position of the protoberberine. Recently we have achieved the biomimetic transformation of protoberberine alkaloid, berberine into benzo[C]phenanthridine alkaloid, chelerythrine.
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