학술저널
L1210 세포에 대한 약용 식물의 세포독성 검색
Screening on Cytotoxicity of Medicinal Plants against L1210 Cell
- 대한약학회
- 약학회지
- 제36권 제5호 (1992년)
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1992.10491 - 495 (5 pages)
- 3
For the research of cytotoxic natural products, 50 medicinal plants were extracted with benzene and methanol, separately, and screened against L1210 cells. From the results(Table I), 6 samples showed cytotoxicity both in benzene and methanol extracts of 17 samples in benzene extracts and 3 samples in methanol extracts, respectively. Generally, the cytotoxicity exhibited high frequency (34%) in benzene extract but low frequency in methanol extract (6%), it meant that active cytotoxic components had less polarity. ED50 values less than 10mcg/ml were observed in 17 medicinal plants.
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