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황색포도상구균의 항생제 다제내성을 갖는 플라스미드의 동정

Characterization of Multidrug Resistant Plasmid of Staphylococcus aureus

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The clinical isolate Staphylococcus aureus SA2 was resistant to ampicillin, chloramphenicol, clindamycin, erythromycin, gentamicin, kanamycin, methicillin, streptomycin, and tobramycin and harboured more than two kinds of plasmids. Transformation experiment demonstrated that 40.98-kb plasmid(pKH2) encoded resistance to ampicillin, clindamycin, erythromycin, kanamycin, and streptomycin. The cleavage map of a pKH2 was determined by restriction enzyme mapping techniques. Cleavage map is given for BamHM, BglI, BstEII, SalI and XhoI.

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