학술저널
Acyclonucleoside류의 합성(7) - 6-아자유리딘의 2'', 3''-seco유도체의 합성 -
Synthesis of Acyclonucleosides - Synthesis of 2'',3''-seco derivatives of 6-Azauridine -
- 대한약학회
- 약학회지
- 제36권 제6호 (1992년)
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1992.12604 - 610 (7 pages)
- 3
Synthesis of 6-aza-2''-azido-2'', 3''-secouridine, 6-aza-2'', 3''-diazido-2'', 3''-secouridine, and 6-aza-5''-azido-2'', 3''-secouridine as potential antiviral agents is described. These acyclic nucleosides were synthesized from uridine by the method of ring opening reaction of sugar moiety. And these compounds were tested against HSV-1 and HSV-2, but the in vitro test results of these compounds were negative.
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