학술저널
피크린 산에 의한 항히스타민제의 추출분광광도 정량
Extraction Spectrophotometric Determination of Antihistamines with Picric Acid
- 대한약학회
- 약학회지
- 제37권 제2호 (1993년)
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1993.04119 - 123 (5 pages)
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A spectrophotometric method is proposed for the determination of antihistamines. The method is based on solvent extraction of the ion pair formed between antihistamines and colored picric acid into chloroform. The binding state of antihistamines-picric acid complexes were presumed by IR and 1H-NMR spectra as intermolecular hydrogen bonding. This method was applicable to the determination of antihistamines in the pharamaceutical preparations.
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