학술저널
N-치환 5-Hydroxyanthranilic acid의 합성
Syntheisis of N-Substituted 5-Hydroxyanthranilic Acid
- 대한약학회
- 약학회지
- 제37권 제3호 (1993년)
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1993.06243 - 246 (4 pages)
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Six N-substituted-5-hydroxyanthranilic acids were synthesized by the coupling reaction of 5-tosyloxyanthranilic acid ethyl ester with corresponding acid chlorides. The structure of the obtained compounds was proved by NMR and IR. These compounds did not inhibit the growth of micro-organisms while suppressed HSV-1 replication in vero cell at 100mcg/ml.
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