학술저널
HPLC를 이용한 뇨 및 혈액중 Metocurine Iodide의 미량분석
Microanalysis of Metocurine Iodide in Urine and Blood by HPLC
- 대한약학회
- 약학회지
- 제38권 제4호 (1994년)
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1994.08379 - 388 (10 pages)
- 16
A new method for the analysis of metocurine iodide in biological fluids was developed. Metocurine iodide was quantitatively extracted with rose bengal from aqueous layer into dichloromethane layer and the amount of metocurine iodide was calculated from the amount of rose bengal which was determined by HPLC with fluorescence detector. It was possible to analyze metocurine iodide without the effect of co-prescribed drugs in the concentration range of 0.09~9.10mcg/ml. The detection limits of metocurine iodide in urine and blood were 0.8 and 1.2ng at S/N=3, each respectively.
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