소갈증 치료제가 실험적 당뇨 흰쥐에 미치는 영향 -청심연자음, 가미조위승기탕, 기국지황탕-

The Effect of Some Antipolydipsia Oriental Prescriptions on Experimental Diabetic Rats -Cheongsimyeonja-eum, Kamijowiseunki-tang, Kikukjihwang-tang

In order to study the effect of some oriental prescriptions for polydipsia on experimental diabetes mellitus and cataract, Cheongsimyeonja-eum, Kamijowiseungki-tang and Kikukjihwang-tang were administered to streptozotocin(STZ)-induced diabetic and galactose-induced cataractous rats. The increased level of serum glucose and urea nitrogen owing to STZ were significantly decreased by administration of Cheongsimyeonja-eum, Kamijowiseungki-tang and Kikukjihwang-tang. The increased level of serum triglyceride and total cholesterol owing to STZ were significantly decreased by administration of Kamijowiseungki-tang and Kikukjihwang-tang. Reduction of body weight owing to STZ was significantly recovered in 7th day since administration of Cheongsimyeonja-eum and Kamijowiseungki-tang. Weight of liver was significantly recovered by administration of Cheongsimyeonja-eum and Kikukjihwang-tang and weight of kidney was significantly recovered only by administration of Kikukjihwang-tang. The polydipsia of water and food were significantly decreased by administration of Cheongsimyeonja-eum, Kamijowiseungki-tang and Kikukjihwang-tang. Onset of cataract in experimental group owing to galactose was not significantly different from control group.