학술저널
D-1,3-Dioxolane 및 D-1,3-Oxathiolane 피리미딘 뉴크레오사이드의 합성
Synthesis of D-1,3-Dioxolane and D-1,3-Oxathiolane Pyrimidine Nucleosides
- 대한약학회
- 약학회지
- 제38권 제6호 (1994년)
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1994.12703 - 711 (9 pages)
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We synthesized D-1,3-dioxolanyl acetate from D-mannose using Frazer-Reide reaction and D-1,3-oxathiolanyl acetate from either D-mannose or D-galactose in good yields. These acetates were conjugated with various disilylated pyrimidine base using trimethylsilyl trifluoromethane sulfonate as a Lewis acid catalyst to obtain 32 different D-nucleosides.
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