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카바프로스타싸이클린 중간체의 합성: 1-Alkoxy-benzenesulfonyl-cyano-4-ethenyl cyclopeptane의 입체선택적 합성

Synthesis of an Intermediate for Carbaprostacyclin: Stereoselective Synthesis of 1-Alkoxy-3-benzenesulfonyl-3-cyano- 4-ethenyl cyclopentane

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An efficient and stereoselective synthetic route to the trisubstituted hydroxy cyclopentane as an useful synthetic intermediate for carbaprostacyclin is described. Pd(O)-mediated intramolecular alkylation of allylic carbonate has been employed as a key reaction.

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