학술저널
인삼의 diol계 사포닌으로부터 새로운 배당체 (20E)-Ginsenoside Rh3 및 그의 입체이성체의 제조와 구조 결정
Preparation and Structure Determination of a New Glycoside, (20E)-Ginsenoside Rh3, and its isomer from Diol-type Ginseng Saponins
- 대한약학회
- 약학회지
- 제39권 제1호 (1995년)
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1995.0285 - 93 (9 pages)
- 6
Acidic and alkaline hydrolysis of diol-type ginseng saponins produced a new glycoside, (20E)-ginsenoside Rh3, and its stereoisomer (20Z)-, which were further subjected to alkaline hydrolysis to give their aglycones, (20E)- and (20Z)-3beta, 12beta-dihydroxy-dammar-20(22),24-diene. The ratio of stereoisomeric mixtures was estimated to be ca. 5 : 1 from intensities of the peaks in 1H- and 13C-NMR spectra. The 1H- and 13C-NMR signals of ginsenoside Rh3, which have remained unclarified, were completely assigned by the extensive application of modern NMR techniques.
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