학술저널
괄루근으로부터 추출한 다당류의 항당뇨활성 및 당뇨성 쥐의 글루타치온대사에 미치는 영향
Effect of Polysaccharide from Trichosanthes kirilowii on Antidiabetic Activity and Glutathione Metabolism in Hyperglycemic Rats
- 대한약학회
- 약학회지
- 제39권 제5호 (1995년)
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1995.10528 - 534 (7 pages)
- 12
This investigation was aimed at the study of the antidiabetic activity and effect on hepatic glutathione metabolism of polysaccharide from Trichosanthes kirilowii in hyperglycemic rats with alloxan (175mg/Kg, i.p.). As the results, the polysaccharide inhibited the increase of blood glucose, triglyceride level and lactate dehydrogenase activity, but cholesterol did not change. And it increased protein bound-SH, nonprotein bound-SH, glutathione level and inhibited the decrease of glutathione S-transferase.
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