췌장소도세포와 면역세포에 미치는 팔미원의 영향

Effects of PALMIWON on Cell Viability of Immune Cell and beta-cell

In order to investigate the usability of PALMIWON as antidiabetic immuno-modulating prescription for Insulin-dependent diabetes, we studied the effects of PALMIWON on immune cell and beta-cell. U937 was used as the model of immune cell and RINm5F as the model of beta-cell. The effects of PALMIWON was measured by cell viability in terms of MTT assay. As a result, PALMIWON and the compositional drugs showed the different effects on immune cell and beta-cell. Cell viability of U937 was significantly decreased whereas that of RINm5F was not significantly different from drug treated group and control, or significantly less reduction compared with U937. It implies that PALMIWON is useful as immunotherapeutic agents in the prevention and therapy of type 1 diabetes.