학술저널
방선균 분리주 No. 2511-5로부터 포스포리파제 C 저해물질 스코파훈진의 분리
Isolation of Scopafungin, a Potent Inhibitor of Phospholipase C from Actinomycetes isolate No. 2511-5
- 대한약학회
- 약학회지
- 제39권 제5호 (1995년)
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1995.10554 - 559 (6 pages)
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MT 2511-5 was purified as a inhibitor of phospholipase C(PLC) from culture broth of a Streptomyces sp. NO. 2511-5. It was identified as scopafungin, 36-membered marcrolide by physicochemical and spectroscopic data. Its IC50 was 30mcM against phospholipase C and it also showed inhibitory activity against some fungi.
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