위령선의 성분연구(제2보) Clematis brachyura Maxim의 flavone에 대하야

Studies on Constituents of RADIX CLEMATIDIS(II) -Isolation of Flavons of the Leaves of Clematis brachyura Maxim

Two flavons, which are a new flavon (the Authors are going to call it "CLEMATISIN") and a yellow crystalline flavon, are isolated from leaves of clematis brachura, Maxim. Clamatisin: A colorless needle crystal which has a slightly sweet taste, mp 225oC (decomp). It is positive(cherry red) for the Mg-HCL(Hg)reaction and is positive(purple) for FeCL3 reagent. It is soluble easily in methanol, ether, acetone, prydine, ethylacetate, hot water and alkali-solutions. It is soluble slightly in cold water and is insoluble in chloroform, benzene and toluene. According to the results of elementary analysis and molecular weight determination the formula of clematisin agrees with C18H18O7. When dried at 80oC., crystalline clematisin (from water) contains one molecule of crystalline water. The following derivatives are prepared; Clematisin-oxim; a colorless needle crystal, mp 215-216oC Clematisin methylate; prepared by diazomethan. mp 191-192oC., a colorless needle crystal. Acethylmethylate; a colorless powder. It is not sharp in melting point and melts at approximately 215oC. Yellow Crystalline Flavon; mp 285-286oC (deco-mp.), yellow needle crystal. It has a slightly sweet teste and shows positive reaction (red) against Mg-HCL(Hg) reaction. Acetate; a colorless needle crystal, mp 168oC.