5-Chloro-8-Quinolinol 유도체의 항아메바 증제로서의 동물실험

Animal Tests of New 5-Chloro-8-quinolinol Derivatives as Amebicides

Three new 5-chloro-8-quinolinol derivatives such as 5-chloro-7-(4-(2-N-pyrrolidylethyl)-l-piperidylmethyl]-8-quinolinol 5-chloro-7- (4-(2-N-piperidylethyl)-l-piperidylmethyl)-8-quinolinol and 5-chloro-7-(2-N-morpholinylethyl)-l-piperidylmethyl)-8-quinolinol were synthesized and found to be effective against Entamoeba histolytica in vitro and against experimental intestinal amebiasis in rats.

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