학술저널
Ester형 Chloramphenicol의 생체내 대사에 대하여
Metabolic fate of chloramphenicol-ester
- 대한약학회
- 약학회지
- 제8권 제1호 (1964년)
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1964.031 - 5 (5 pages)
- 0
Present experiment in vivo shows that some conversions of active groups in chloramphenicol residue of ester, that is hydrolytic cleavage of dichloracetamide and glucuronide formation, seem to take place prior to hydrolysis. This result suggest that the enzymatic hydrolysis rate in vitro, is not available as an index for the evaluation of the chloramphenicol ester potency.
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