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학술저널

참당귀근의 Coumarin 성분에 관한 연구(I)

Studies on the Coumarins of the Root of Angelica gigas NAKAI (I)

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From the root of Angelica gigas NAKAI (Umbelliferae), known as "Tang Gui" in Korea, substance A (colorless needle crystal, C14H14O4, m.p. 178o) and B (white plate crystal, C19H20O5, m.p. 111o) were obtained. Acetylation of "A" gave its monoacetate, white needles, C16H16O5. Saponification of "B" with 5% sodium hydroxide produced "A" and senecionic acid. Examination using I.R. and N.M.R. spectra shows that "A" is identical with decursinol and that "B" with decursin. The root also appears to contain five coumarin derivatives and two steroidal compounds.

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