학술저널
제암성물질의 합성 및 항종양시험에 관한 연구 IV N-치환, p-Arsanilic Acid 유도체의 합성 및 항종양시험
Studies on the Synthesis and Antitumor Actiities of Potential Antineoplastic Agents. IV. Synthesis and Antitumor Activities of N-Substituted-p-Arsanilic Acid
- 대한약학회
- 약학회지
- 제15권 제1호 (1971년)
-
1971.0316 - 23 (8 pages)
- 0
Seven organic arsine compounds are synthesized as potential anti-tumor agents are subjected to the screening test of activity against SN-36 Leukemia, Sarcoma 180 and Ehrlich ascites carcinoma. Three compounds, namely N-(5-Nitrofroyl)-p-arsanilic acid. N-(2,4-Dihydroxybenzoethyl)-p-arsanilic acid and N-alpha(p-arsanilide)acetyl thiourea of the all synthesized compounds showed comparatively potential activities against experimental ascitic tumors both through cytological findings and survival duration.
(0)
(0)