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Isatin과 일염기산의 반응

The Reaction of Isatin with Monocarboxylic Acids

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On heating isatin with aromatic rnonocarboxylic acids having alpha-hydrogen atoms such as p-nitrophenylacetic acid, p-methoxyphenyl acetic acid and alpha-naphthylacetic acid in the presence of anhydrous sodium acetate functioning as a catalyst, p-nitrobenzylidene-3-oxindole, p-methoxybenzylidene-3-oxindole and alpha-naphthobenzylidene-3-oxindole are obtained, respectively. The results of these experiments show that isatin may be used as the carbonyl component in the condensation reaction.

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