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납중독에 있어서 delta-Aminolevulinic Acid Dehydratase 활성에 미치는 Ascorbic Acid 및 Methionine의 효과에 관한 연구

The Influence of Ascorbic Acid and Methionine on the delta-Aminolevulinic Acid Dehydratase Activity in Lead Poisoning.

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the activity of delta-aminolevulinic acid debydratase(ALAD) in red cell of rabbit inhibited by addition of Pb(Ac)2 was recovered by ascorbic acid and methionine. Although the administration of Pb(AC)2 (50mg/kg) to rabbit caused to diminish completely the ALAD activity in blood within 2 hr. Pretreatment of ascorbic acid and methionine decreased this inhibitory action. Pretreatment of ascorbic acid also decreased the increment of delta-aminolevulinic acid output in urine by lead poisoning.

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